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Broad Institute Inc snp annotation and proxy search tool snap
Snp Annotation And Proxy Search Tool Snap, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/snp+annotation+and+proxy+search+(snap)+tool/snp+annotation+and+proxy+search/med_rxiv__2023__02__23__23286339-34-9-16
Average 90 stars, based on 1 article reviews
snp annotation and proxy search tool snap - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Northern Blot:

Article Title: The PPAR Alpha gene is associated with triglyceride, low-density cholesterol, and inflammation marker response to fenofibrate intervention: The GOLDN Study
Article Snippet: This may relate to the different variants typed in our study, where the closest is 170,0048 bp downstream of variant rs4253778 (SNP Annotation and Proxy Search (SNAP) software tool by the Broad Institute ( http://www.broadinstitute.org/mpg/snap/ldsearch.php ) which uses HapMap Project data, reports that none of our SNPs are in LD with an r 2 >0.8 with rs4253778).

Article Title: Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings
Article Snippet: In this study, we have demonstrated the utility of two publicly available bioinformatics tools, Broad Institute's SNP Annotation and Proxy search (SNAP) tool ( http://www.broadinstitute.org/mpg/snap/ ) and RegulomeDB ( http://regulomedb.org ) , to investigate potential regulatory functions of recently identified, non- APOE variants (index and proxy SNPs) for known and suggestive loci associated with risk and AAO of LOAD.

Article Title: Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations.
Article Snippet: Genome‐Wide Association Studies (GWAS) have identified an abun‐ dance of single nucleotide polymorphisms (SNPs) associated with disease phenotypes, but clinical understanding remains limited.. These discoveries provide important insights into the genetic archi‐ tecture of complex traits while also providing new opportunities to understand the biology of complex diseases.. Allele‐specific analyses to understand frequency differences between populations, partic‐ ularly populations not well studied, are important to help identify genetic variants that may have been affected by natural selection or which may have a functional effect on disease mechanisms and phenotypic predisposition, motivating new GWA studies in more di‐ verse populations around the world to enable novel genetic findings to aid the development of new therapies to reduce morbidity and mortality.

Article Title: Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm
Article Snippet: Linkage disequilibrium was assessed by querying the 70 SNPs using Broad Institute's SNP Annotation and Proxy Search (SNAP) tool in the CEU (Utah residents with Northern and Western European ancestry) with R 2 threshold of 0.8 and distance limit of 500 , .

Article Title: An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
Article Snippet: Where primary SNPs of interest were not available on this array, the Broad Institute SNP Annotation and Proxy Search (SNAP) tool was used to identify proxy SNPs (SNPs which can represent the primary SNP of interest) with a minimum linkage disequilibrium r 2 ≥0.6 [ ].

Western Blot:

Article Title: The PPAR Alpha gene is associated with triglyceride, low-density cholesterol, and inflammation marker response to fenofibrate intervention: The GOLDN Study
Article Snippet: This may relate to the different variants typed in our study, where the closest is 170,0048 bp downstream of variant rs4253778 (SNP Annotation and Proxy Search (SNAP) software tool by the Broad Institute ( http://www.broadinstitute.org/mpg/snap/ldsearch.php ) which uses HapMap Project data, reports that none of our SNPs are in LD with an r 2 >0.8 with rs4253778).

Article Title: Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings
Article Snippet: In this study, we have demonstrated the utility of two publicly available bioinformatics tools, Broad Institute's SNP Annotation and Proxy search (SNAP) tool ( http://www.broadinstitute.org/mpg/snap/ ) and RegulomeDB ( http://regulomedb.org ) , to investigate potential regulatory functions of recently identified, non- APOE variants (index and proxy SNPs) for known and suggestive loci associated with risk and AAO of LOAD.

Article Title: Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations.
Article Snippet: Genome‐Wide Association Studies (GWAS) have identified an abun‐ dance of single nucleotide polymorphisms (SNPs) associated with disease phenotypes, but clinical understanding remains limited.. These discoveries provide important insights into the genetic archi‐ tecture of complex traits while also providing new opportunities to understand the biology of complex diseases.. Allele‐specific analyses to understand frequency differences between populations, partic‐ ularly populations not well studied, are important to help identify genetic variants that may have been affected by natural selection or which may have a functional effect on disease mechanisms and phenotypic predisposition, motivating new GWA studies in more di‐ verse populations around the world to enable novel genetic findings to aid the development of new therapies to reduce morbidity and mortality.

Article Title: Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm
Article Snippet: Linkage disequilibrium was assessed by querying the 70 SNPs using Broad Institute's SNP Annotation and Proxy Search (SNAP) tool in the CEU (Utah residents with Northern and Western European ancestry) with R 2 threshold of 0.8 and distance limit of 500 , .

Article Title: An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
Article Snippet: Where primary SNPs of interest were not available on this array, the Broad Institute SNP Annotation and Proxy Search (SNAP) tool was used to identify proxy SNPs (SNPs which can represent the primary SNP of interest) with a minimum linkage disequilibrium r 2 ≥0.6 [ ].

Variant Assay:

Article Title: The PPAR Alpha gene is associated with triglyceride, low-density cholesterol, and inflammation marker response to fenofibrate intervention: The GOLDN Study
Article Snippet: This may relate to the different variants typed in our study, where the closest is 170,0048 bp downstream of variant rs4253778 (SNP Annotation and Proxy Search (SNAP) software tool by the Broad Institute ( http://www.broadinstitute.org/mpg/snap/ldsearch.php ) which uses HapMap Project data, reports that none of our SNPs are in LD with an r 2 >0.8 with rs4253778).

Article Title: Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings
Article Snippet: In this study, we have demonstrated the utility of two publicly available bioinformatics tools, Broad Institute's SNP Annotation and Proxy search (SNAP) tool ( http://www.broadinstitute.org/mpg/snap/ ) and RegulomeDB ( http://regulomedb.org ) , to investigate potential regulatory functions of recently identified, non- APOE variants (index and proxy SNPs) for known and suggestive loci associated with risk and AAO of LOAD.

Article Title: Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations.
Article Snippet: Genome‐Wide Association Studies (GWAS) have identified an abun‐ dance of single nucleotide polymorphisms (SNPs) associated with disease phenotypes, but clinical understanding remains limited.. These discoveries provide important insights into the genetic archi‐ tecture of complex traits while also providing new opportunities to understand the biology of complex diseases.. Allele‐specific analyses to understand frequency differences between populations, partic‐ ularly populations not well studied, are important to help identify genetic variants that may have been affected by natural selection or which may have a functional effect on disease mechanisms and phenotypic predisposition, motivating new GWA studies in more di‐ verse populations around the world to enable novel genetic findings to aid the development of new therapies to reduce morbidity and mortality.

Article Title: Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm
Article Snippet: Linkage disequilibrium was assessed by querying the 70 SNPs using Broad Institute's SNP Annotation and Proxy Search (SNAP) tool in the CEU (Utah residents with Northern and Western European ancestry) with R 2 threshold of 0.8 and distance limit of 500 , .

Article Title: An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
Article Snippet: Where primary SNPs of interest were not available on this array, the Broad Institute SNP Annotation and Proxy Search (SNAP) tool was used to identify proxy SNPs (SNPs which can represent the primary SNP of interest) with a minimum linkage disequilibrium r 2 ≥0.6 [ ].

Software:

Article Title: The PPAR Alpha gene is associated with triglyceride, low-density cholesterol, and inflammation marker response to fenofibrate intervention: The GOLDN Study
Article Snippet: This may relate to the different variants typed in our study, where the closest is 170,0048 bp downstream of variant rs4253778 (SNP Annotation and Proxy Search (SNAP) software tool by the Broad Institute ( http://www.broadinstitute.org/mpg/snap/ldsearch.php ) which uses HapMap Project data, reports that none of our SNPs are in LD with an r 2 >0.8 with rs4253778).

Article Title: Connecting the Dots: Potential of Data Integration to Identify Regulatory SNPs in Late-Onset Alzheimer's Disease GWAS Findings
Article Snippet: In this study, we have demonstrated the utility of two publicly available bioinformatics tools, Broad Institute's SNP Annotation and Proxy search (SNAP) tool ( http://www.broadinstitute.org/mpg/snap/ ) and RegulomeDB ( http://regulomedb.org ) , to investigate potential regulatory functions of recently identified, non- APOE variants (index and proxy SNPs) for known and suggestive loci associated with risk and AAO of LOAD.

Article Title: Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations.
Article Snippet: Genome‐Wide Association Studies (GWAS) have identified an abun‐ dance of single nucleotide polymorphisms (SNPs) associated with disease phenotypes, but clinical understanding remains limited.. These discoveries provide important insights into the genetic archi‐ tecture of complex traits while also providing new opportunities to understand the biology of complex diseases.. Allele‐specific analyses to understand frequency differences between populations, partic‐ ularly populations not well studied, are important to help identify genetic variants that may have been affected by natural selection or which may have a functional effect on disease mechanisms and phenotypic predisposition, motivating new GWA studies in more di‐ verse populations around the world to enable novel genetic findings to aid the development of new therapies to reduce morbidity and mortality.

Article Title: Genomic risk prediction of aromatase inhibitor‐related arthralgia in patients with breast cancer using a novel machine‐learning algorithm
Article Snippet: Linkage disequilibrium was assessed by querying the 70 SNPs using Broad Institute's SNP Annotation and Proxy Search (SNAP) tool in the CEU (Utah residents with Northern and Western European ancestry) with R 2 threshold of 0.8 and distance limit of 500 , .

Article Title: An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank
Article Snippet: Where primary SNPs of interest were not available on this array, the Broad Institute SNP Annotation and Proxy Search (SNAP) tool was used to identify proxy SNPs (SNPs which can represent the primary SNP of interest) with a minimum linkage disequilibrium r 2 ≥0.6 [ ].



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